Pharmacodynamic adaptive system controlling the depth of anaesthesia


 – Istituto Nazionale dei Tumori –

The invention relates to an algorithm for controlling hypnotic and opioid level throughout the entire control task of General Anaesthesia.

In particular, the invention implements a series of steps which allows to optimize the anaesthesia level for the induction and maintenance of a balanced anaesthesia.


  • The system is applicable to all surgical procedures that require general anesthesia.
  • Decision support system designed to model the entire process of GA control task.

Key benefits

  • Provides anaesthesiologists with the optimal drug infusion recommendation.
  • Allows better personalised approach with higher reproducibility.
  • Reduces workload and increase clinician vigilance.


  • Licensing out.
  • Co-Development.

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